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Coffee May Protect Against Gallstones

Drinking more coffee may help reduce the risk of developing gallstones, according to a new study published in the Journal of Internal Medicine.

Among 104,493 individuals, those who drank more than six cups of coffee per day had a 23% lower risk of developing symptomatic gallstones compared with individuals who did not drink coffee. Drinking one extra cup of coffee per day was associated with 3% lower risk. Also, individuals with certain genetic variants that have been linked to increased coffee consumption had a lower risk of gallstones.

Although the study only uncovered correlations, the authors highlighted several mechanisms by which coffee consumption might help prevent gallstones from forming.

Nordestgaard AT, et al. (2019). Coffee intake protects against symptomatic gallstone disease in the general population: a Mendelian randomization study. Journal of Internal Medicine; https://doi.org/10.1111/joim.12970.

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