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Fibre-rich Diet Linked to Lowered Risk of Painful Knee Osteoarthritis

Findings from two long-term studies in line with other associated health benefits of fibre.

A fibre-rich diet is linked to a lowered risk of painful knee osteoarthritis, finds the first study of its kind, published online in the Annals of the Rheumatic Diseases.

The findings, which draw on two different long-term studies, are broadly in line with the other reported health benefits of a fibre-rich diet. These include reductions in blood pressure, weight, and systemic inflammation, and improved blood glucose control.

The researchers mined data from two US studies in a bid to find out if dietary fibre might have any bearing on the risks of x-ray evidence of knee osteoarthritis, symptomatic knee osteoarthritis (x-ray evidence and symptoms, such as pain and stiffness), and worsening knee pain.

The first of these studies was the Osteoarthritis Initiative (OAI). This has been tracking the health of nearly 5000 US men and women with, or at risk of, osteoarthritis since 2004-6 (average age 61), to pinpoint potential risk factors for the condition.

The second was part of the Framingham Offspring cohort study, which has been tracking the health of more than 1200 adult children of the original Framingham Heart Study and their partners since 1971. For the current study, results are based on data first taken between 1993-4, when participants were 54, on average, up to 2002-5.

For both studies, dietary fibre intake was measured using Food Frequency Questionnaire responses. It averaged out at around 15 g daily in the OAI, and 19 g daily in the Framingham Offspring, study.

Information on symptoms and x-ray evidence were collected every year for four years in the OAI and assessed after nine years in the Framingham Offspring study. Data were also gathered on potentially influential factors, such as knee injury/surgery, medication, and lifestyle, including tobacco and alcohol use and physical exercise.

At the end of four years, among the 4051 participants in the OAI with complete data on dietary fibre intake, 869 knees were symptomatic; 152 displayed x-ray evidence of osteoarthritis; and pain had worsened in 1964.

After an average of nine years, among 971 participants in the Framingham Offspring study with complete dietary fibre data, 143 knees were symptomatic and 175 displayed x-ray evidence of osteoarthritis.

Analysis of the data showed that eating more fibre was associated with a lower risk of painful knee osteoarthritis. Compared with the lowest intake (bottom 25% of participants), the highest intake (top 25%) was associated with a 30% lower risk in the OAI and a 61% lower risk in the Framingham study. But it was not associated with x-ray evidence of knee osteoarthritis.

Additionally, among the OAI participants, eating more fibre in general, and a high cereal fibre intake, were associated with a significantly lower risk of worsening knee pain.
These findings held true, regardless of other potentially influential factors.

This is an observational study, so no firm conclusions can be drawn about cause and effect. Nevertheless, the researchers say: "These data demonstrate a consistent protective association between total fibre intake and symptom-related knee [osteoarthritis] in two study populations with careful adjustment for potential confounders."

And they point to other evidence suggesting that a fibre-rich diet is associated with several health benefits, many of which are relevant to osteoarthritis.

Dietary intake of fibre and risk of knee osteoarthritis in two US prospective cohorts. Annals of the Rheumatic Diseases; http://ard.bmj.com/content/early/2017/05/04/annrheumdis-2016-210810

Read 816 times Last modified on Wednesday, 24 May 2017 10:56

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