New data presented by Nestlé Health Science at the 2018 Annual Meeting of the European Academy of Allergy and Clinical Immunology (EAACI) revealed high variability, including batch-to-batch inconsistencies, in the protein make-up of products specially formulated for infants with cows' milk protein allergy (CMA), which may impact their efficacy and lead to significantly less tolerance.1 The research further substantiates that "not all commercially available products for infants with CMA are safe and effective."2
"Breastfeeding remains the best nutrition for a baby, but specialist infant formulas are required to dietary manage CMA when breastfeeding is not possible," says Dr Sophie Nutten, Institute of Nutritional Science, Nestlé Research Center, Switzerland. "Ensuring patient safety and efficacy is key for us and our extensively hydrolysed formula, Althéra®. We have however become increasingly aware of other extensively hydrolysed formulas which are labelled as hypoallergenic but have high residual protein content and insufficient evidence. Patient safety and efficacy should always be given the highest priority in the design of specialist hypoallergenic infant formulas and the safety and efficacy should not just focus on the clinical trial stage, but be carried through to the patient, to ensure consistency and quality in production over time."
For more detail on the first analysis presented click here.
References: 1. Nutten S, Järvi A., Maynard F, et al. Extensively Hydrolyzed Formulas for the Management of Cow's Milk Protein Allergy in Infants: Is Extensive Hydrolysis Sufficient to Guarantee Success? Presented at European Academy of Allergy and Clinical Immunology Annual Meeting, Sunday 27th May 2018.; 2. Meyer R, Kulslys M, Muraro A, et al. Controversies on special products for managing cow's milk protein allergy in infants: safety and suitability. EAACI symposium, 18 June 2017, Helsinki, Finland. Proceedings published in EMJ Allergy & Immunology, 2017; 2(1): 46–51.
Mothers should be encouraged to continue breastfeeding even when their infants have cows' milk protein allergy. Althéra® is a formula for special medical purposes and must only be used under strict medical supervision and after full consideration of the feeding options available, including breastfeeding. For healthcare professionals only.