Patients Regain Weight Rapidly After Stopping Weight Loss Drugs, but Still Keep Off a Quarter of Weight Lost

A year after stopping taking weight loss drugs such as Ozempic and Wegovy, people regain on average 60% of their lost weight – but beyond this, their weight regain is likely to plateau, with individuals managing to keep off 25% of the weight lost to treatment, say researchers at the University of Cambridge.

Brajan Budini, a medical student at the School of Clinical Medicine and Trinity College, University of Cambridge, said: “Our projections show that even though people regain most of the weight they have lost, they still maintain some of the weight loss, but what we currently don’t know is if the same proportion of lean mass is recovered. If the regained weight is disproportionately fat, individuals may ultimately be worse off than before in their fat-to-lean mass ratio, which may have adverse consequences for their health.”

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